Research Articles
Correcting Baseline Drift in UV-Vis Spectroscopy: A Complete Guide for Robust Pharmaceutical Analysis
This article provides a comprehensive guide for researchers and drug development professionals on addressing baseline drift in UV-Vis spectroscopy.
UFLC-DAD in High-Throughput Screening: Accelerating Drug Discovery and Bioanalysis
Ultra-Fast Liquid Chromatography with Diode Array Detection (UFLC-DAD) has emerged as a pivotal analytical technique for high-throughput screening (HTS) in modern drug discovery and development.
UFLC-DAD in Pharmaceutical Analysis: Practical Applications, Method Development, and Validation for Modern Labs
This article provides a comprehensive overview of the practical applications of Ultra-Fast Liquid Chromatography with Diode Array Detection (UFLC-DAD) in pharmaceutical analysis.
Robustness Testing in Comparative Method Validation: A Strategic Guide for Pharmaceutical Scientists
This article provides a comprehensive guide to robustness testing within comparative analytical method validation, tailored for researchers and drug development professionals.
Navigating Global Validation Guidelines: A Comparative Analysis of ICH, EMA, and WHO Requirements for Pharmaceutical Professionals
This article provides a comprehensive comparative analysis of analytical and process validation guidelines from the ICH, EMA, and WHO.
A Strategic Framework for Designing Robust Method Comparison Studies in Assay Validation
This article provides a comprehensive, step-by-step guide for researchers and drug development professionals on designing and executing method comparison studies, a critical component of assay validation.
Optimized Liquid-Liquid Extraction Protocol for UFLC-DAD Analysis: A Comprehensive Guide from Method Development to Validation
This article provides a complete framework for developing and optimizing liquid-liquid extraction (LLE) protocols specifically for Ultra-Fast Liquid Chromatography with Diode Array Detection (UFLC-DAD) analysis.
Advanced UV-Visible Spectrophotometric Method Development and Validation for Paracetamol Tablet Analysis
This article provides a comprehensive guide for researchers and pharmaceutical scientists on developing and validating robust UV-Visible spectrophotometric methods for paracetamol analysis in tablet formulations.
Beyond Electrospray: Advanced Strategies to Solve Poor Ionization of Non-Polar Compounds in Mass Spectrometry
The analysis of non-polar compounds by mass spectrometry remains a significant challenge due to their poor ionization efficiency with conventional electrospray ionization (ESI).
A Systematic Guide to Optimizing ESI Ionization Voltage for Enhanced LC-MS Sensitivity and Reproducibility
This article provides a comprehensive guide for researchers and analytical scientists on optimizing electrospray ionization (ESI) voltage in liquid chromatography-mass spectrometry (LC-MS).